Charge-Induced Patchy Attractions between Proteins
نویسندگان
چکیده
منابع مشابه
Confinement-induced colloidal attractions in equilibrium.
The Poisson-Boltzmann theory for colloidal electrostatic interactions predicts that charged colloidal spheres dispersed in water should repel each other, even when confined by charged surfaces. Direct measurements on highly charged polystyrene spheres, however, reveal strong, long-ranged confinement-induced attractions that have yet to be explained. We demonstrate that anomalous attractions als...
متن کاملDramatic influence of patchy attractions on short-time protein diffusion under crowded conditions
In the dense and crowded environment of the cell cytoplasm, an individual protein feels the presence of and interacts with all surrounding proteins. While we expect this to strongly influence the short-time diffusion coefficient Ds of proteins on length scales comparable to the nearest-neighbor distance, this quantity is difficult to assess experimentally. We demonstrate that quantitative infor...
متن کاملHydrodynamic pair attractions between driven colloidal particles.
Colloidal spheres driven through water along a circular path by an optical ring trap display unexpected dynamical correlations. We use Stokesian dynamics simulations and a simple analytical model to demonstrate that the path's curvature breaks the symmetry of the two-body hydrodynamic interaction, resulting in particle pairing. The influence of this effective nonequilibrium attraction diminishe...
متن کاملForthcoming attractions
Sequence analysis The hot topic in sequence analysis is hidden Markov models (HMMs). Rather than looking at related protein sequences as clusters of pairwise alignments, HMMs abstract from a family of related sequences a probability model that can be used to predict whether a novel sequence is a member of the family. Some nifty mathematics are needed for accurate HMMs, but once created they can...
متن کاملAttractions between Hard Colloidal Spheres in Semiflexible Polymer Solutions
We explore the depletion attractions that arise between hard colloidal spheres immersed in a nonadsorbing polymer solution of DNA. We spatially confine two 1.25 μm silica spheres in a scanning optical tweezer and quantitatively examine their interaction potential in double-stranded DNA solutions of different concentrations. The potentials obtained display variations in depth and range that are ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2015
ISSN: 1520-6106,1520-5207
DOI: 10.1021/jp512027j